Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (1027)   No Age Effect (543)  
  • Study type: + -
    GWAS (2)   ‑ (27)   Candidate Region/Gene (784)   Meta‑Analysis (38)   Complete Mitochondrial Genome (2)   Whole‑Genome Linkage Scan (1)   Genome‑Wide Association Study (710)   Mitochondrial Haplogroup (36)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP (572)   Locus (5)   Haplotype (87)   Other (1)   STR (11)   Deletion (5)   CNV (1)    (1)   VNTR (1)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
    Export results (Download)

    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs2292664 RIMBP2 — 1.4e-37 5036 — American 28-70 CC, CG GG Genome-Wide Association Study 22174011
    rs10771498 FAR2 (upstream) 0.92 1.35e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — T Genome-Wide Association Study 21782286
    rs10778652 CORO1C 1.08 2.18e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — C — Genome-Wide Association Study 21782286
    Not specified IFNG — 0.05 707 vs 339 — Turkish, Polish, Italian, Bulgarian Age range: 65-99 — — Candidate Region/Gene 21299522
    rs7959761 SSPN 1.00 9.56e-05 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs3782415 SOCS2 1.38 0.000284992 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs1922263 CHST11 1.17 0.003569024 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
    rs2232548 KLRF1 1.15 0.008366096 801 vs 914 — Caucasian Median age 104 A C Genome-Wide Association Study 22279548
    Cdx2–GATA haplotypes VDR — 0.05 923 — Dutch Mean age 75.7 GG GA, AA Candidate Region/Gene 21051524

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue