Loss-of-function mutations in daf-6 extend lifespan by up to 50% [10617200]. daf-6 mutants are dauer defective, chemotaxis defective, osmotic aviodance (osm), male mate poorly, and, dye filling defective [2428682]. Mutants of daf-6 have defective sheath cells causing the amphid and phasmids pores to be closed.
Mean: +50
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