LYS9

Symbol: LYS9
Name: LYSine requiring 9
Alias: LYS13
Entrez gene ID: 855786
Ensembl gene ID: YNR050C
Species: Yeast (Taxid: 4932)

Functional description:
Lys9p; Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112 [Source:SGD;Acc:S000005333] [Ensembl]

Observation:

Deletion of LYS9 increases replicative lifespan [16293764]. LYS9 deletion increases replicative lifespan by 20% in the alpha strain [19030232].



Interventions:
  • LYS9 deletion +20%

  • Assays: Replicative Lifespan

    Classification:
  • Gerontogene
  • Positive Gerontogene


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • AASS (9606)
  • AASS (9598)
  • AASS (9615)
  • AASS (9913)
  • Aass (10090)
  • Aass (10116)
  • AASS (9031)
  • aass (7955)
  • LKR (7227)
  • AgaP_AGAP008632 (7165)
  • dehydrogenase (6239)
  • SPBC3B8.03 (4896)
  • LYS9 (4932)
  • KLLA0C18744g (28985)
  • GeneID:2678741 (148305)
  • NCU03748 (5141)



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