ARP1

Symbol: ARP1
Name: Actin-Related Protein 1
Alias: ACT5
Entrez gene ID: 856530
Ensembl gene ID: YHR129C
Species: Yeast (Taxid: 4932)

Functional description:
Arp1p; Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin [Source:SGD;Acc:S000001171] [Ensembl]

Observation:

Deletion of ARP1 decreases replicative lifespan by 40% in the alpha strain [18340043; 19030232].



Interventions:
  • ARP1 deletion -40%

  • Assays: Replicative Lifespan

    Classification:
  • Aging-Suppressor
  • Negative Aging-Suppressor


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • ACTR1B (9606)
  • ACTR1B (9598)
  • ACTR1B (9615)
  • Actr1b (10090)
  • actr1 (7955)
  • arp1 (4896)
  • ARP1 (4932)
  • KLLA0E22925g (28985)
  • AGOS_AFR051W (33169)
  • GeneID:2680445 (148305)
  • NCU04247 (5141)



  • Edit \ Update (Admin) | Delete

    Comment on This Data Unit