The frequency of HLA-DQB10503 was significantly increased in the Okinawan centenarians compared to controls. Increased frequency can be explained by a LD with DRBl1401 or vice versa, which was also significantly frequent in them, because DRB11401-DQB10503-DQA1*0104 is one of the prominent haplotypes in Okinawan Japanese.
odds_ratio = RR = 5.196 (could not convert string to float: RR = 5.196)
Ethnicity:Okinawan Age of cases: Mean age 102.3 +/- 1.9 years Shorter lived allele: non-DQB1*0503 alleles Longer lived allele: DQB1*0503
Statistics - Number of cases/controls: 120 vs 129 (initial)
- p-value:
0.0002
[0.0002]
- Significant: Yes
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