rs769449
Polymorphism: rs769449
rs769449
(
SNPedia |
23andMe
)
Variant Type: SNP
Location: 19q13.2
Factor:
- Symbol: APOE
- Name: apolipoprotein E
- Entrez ID: 348
- Ensembl ID: ENSG00000130203
Factors:
APOE
apolipoprotein E
(
348
/
ENSG00000130203
)
Ethnicity:
Danish,
German
Age of cases: 92-93 Danish, 95–110 German
Shorter lived allele: G
Statistics
- Number of cases/controls: 1,089 vs 736 (initial)
| 1,613 vs 1,104 (replication)
- Odds ratio: 0.7
- p-value:
0.018
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Technology: "Illumina GoldenGate, Sequenom MassARRAY
Reference:
22234866: Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.
Choice: Curate
Created: June 30, 2013, midnight
Updated: Aug. 26, 2013, 12:28 p.m.
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