Allele 10 (10 imperfect repeats) shows a remarkable dominant and beneficial effect that reduces the log hazard of death in an additive manner. Detailed OR data is as follows: Heterozygous 10: 0.92, and homozygous 10: 0.851. P-value data: Heterozygous 10: 0.013; homozygous 10*: 0.005.
Other alleles (6, 7, 8, 9, 10) seem to have no significant influence on longevity.
Ethnicity:Italian Age of cases: 100+ Longer lived allele: 10* (imperfect allele 10) Finding: Positive
Statistics - Number of cases/controls: 210 vs 755 (initial)
- Odds ratio: 0.851 - Odds ratio type: Shorter - p-value:
0.005
- Significant: Yes
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