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Denigma
»
Lifespan
»
Variants
» Variant = rs282070
o
|
Admin
Mouse Lifespan Experiments
(
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)
rs282070
Polymorphism:
rs282070
rs282070
(
SNPedia
|
23andMe
)
Location:
6q15
Factor:
- Symbol:
MAP3K7
- Name:
mitogen-activated protein kinase kinase kinase 7
- Entrez ID:
6885
- Ensembl ID:
ENSG00000135341
Factors:
MAP3K7
mitogen-activated protein kinase kinase kinase 7
(
6885
/
ENSG00000135341
)
Description:
Study consisted of two stages (stage 2 only was recorded here)
Ethnicity:
Calabrian
Age of cases:
90+, median 92
Shorter lived allele:
G
Statistics
- Number of cases/controls:
288 vs 554 (initial)
- p-value:
0.0011 [0.0011]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Candidate Region/Gene
- Technology:
allele-specific PCR-based KASPar SNP genotyping system (KBiosciences, Hoddesdon, UK) (Cuppen
Reference:
22576335: MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping.
Choice:
Curate
Created:
July 2, 2013, 2:48 a.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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