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Symbol: Zmpste24 Name: zinc metallopeptidase, STE24 homolog (S. cerevisiae) Entrez gene ID: 230709 Ensembl gene ID: ENSMUSG00000043207 Species: Mouse (Taxid: 10090) Functional description: Metalloproteinase involved in the maturation of lamin A (Lmna); Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C. [UniProt] Observation: Knockout mice exhibit nuclear architecture abnormalities and signs of accelerated ageing. Assays: Organismal Lifespan Classification: Aging Relevance Analysis/Source:  GenAge GenDRHomologs Inparanoids Edit \ Update (Admin) | Delete |
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