Symbol: CG3776 Alias: Dmel\CG3776; DmP29; EP(2)0835; Jhebp29; P29 Entrez gene ID: 37996 Ensembl gene ID: FBgn0035088 Species: Fly (Taxid: 7227) Observation: Both overexpression and underexpression of CG3776 (alias Jhebp29) reduces the mean lifespan, where the reduction in males is slightly higher. The lifespan of male flies with under- and overexpressed CG3776 is reduced by 38.8 and 42.6%, respectively when compared with Oregon R flies.The lifespan of female flies with under- and overexpressed CG3776 is reduced by 31.6 and 35%, respectively when compared to Oregon R flies. Among the males and females, relatively to Oregon R and EP835/CyO, the age-specific survival of EP835/EP835 and EP835/Gal4 is reduced in both log-rank and Wilcoxon tests (P < 0.001); survival of EP835/EP835 and EP835/Gal4 differed using the log-rank-test (male: P<0.001; female: P=0.027) [18275960]. Interventions: Assays: Organismal Lifespan Mean: -31.6 to -42.6 Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Note: Does it require a new category of lifespan factor? How is CG3776 underexpressed. Define the type of intervention. Edit \ Update (Admin) | Delete |
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