Symbol: THC Name: Tetrahydocurcumin Entrez gene ID: 7454 Ensembl gene ID: ENSG00000015285 Species: Human Function: Tetrahydocurcumin (THC) is a curcumin metabolite. Observation: Tetrahydocurcumin extends the lifespan and reduces oxidative stress in male and female fruit flies. THC extends lifespan of Drosophila and inhibits the oxidative stress response by regulating FOXO and Sir2 [22156377]. In male mice supplementation with tetrahydrocurcumin beginning at the age of 13 month increases the mean lifespan by an average of 84 days, i.e. an increase of 11.7% [17516143]. Interventions: Assays: Organismal Lifespan Classification: Type: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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