Symbol: lin-5 Name: abnormal cell LINeage Alias: abnormal cell LINeage family member (lin-5);WBGENE00002994 Entrez gene ID: 174267 Ensembl gene ID: T09A5.10 Species: Worm (Taxid: 6239) Functional description: Essential component of the spindle apparatus required for spindle positioning and chromosome movement. Acts to recruit or anchor gpr-1/gpr-2 complex to the spindle and cortex. Also involved, directly or indirectly, in cytokinesis and in the coupling of DNA replication, centrosome duplication and mitotic division. [UniProt] Observation: lin-5 RNAi in the adulthood extends mean and maximum lifespan by 16 and 9% [23144747]. Interventions: Assays: Organismal Lifespan Mean: +16.4 Maximum: +8.7 Classification: References: Aging Relevance Analysis/Source: Homologs Edit \ Update (Admin) | Delete |
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