Symbol: Coq7 Name: demethyl-Q 7 Alias: mclk1; clk-1 Entrez gene ID: 12850 Ensembl gene ID: ENSMUSG00000030652 Species: Mouse (Taxid: 10090) Functional description: Involved in lifespan determination in ubiquinone- independent manner. Involved in ubiquinone biosynthesis. Potential central metabolic regulator. [UniProt] Observation: Mice heterozygous in Coq7 live about 15 to 30% longer than controls [16195414]. Transgenic overexpression of mouse Coq7 reverts the extended lifespan of clk-1 mutants in C. elegans [11511092]. Interventions: Assays: Organismal Lifespan Mean: +15 to +30 Classification: References: Aging Relevance Analysis/Source: Homologs Orthologs Edit \ Update (Admin) | Delete |
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