Symbol: MDB4 Name: methyl-CpG binding domain protein 4 Entrez gene ID: 8930 Ensembl gene ID: ENSG00000129071 Species: Human (Taxid: 9606) Function: MDB4 can bind to methylated DNA, is linked to DNA repair and mutations and knockdowns of MBD4 leads to increased genomic instability [10097147; 19854937]. Observation: Methylation marker cg27193080 is significantly associated with age and its methylation fraction is influenced by the SNP variantrs140692. Both the SNP and the methylation marker map to the MBD4, with the SNP in an intron and the methylation marker just upstream of the coding region [23177740]. Assays: Organismal Lifespan Classification: References: Aging Relevance Analysis/Source: Homologs Inparanoids Edit \ Update (Admin) | Delete |
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