Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (243)   No Age Effect (314)  
  • Study type: + -
    GWAS (2)   ‑ (1)   Candidate Region/Gene (375)   Meta‑Analysis (37)   Complete Mitochondrial Genome (1)   Genome‑Wide Association Study (147)   Mitochondrial Haplogroup (1)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP « 
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs4859571 NAAA — 1.56e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs7803143 PSCD3 — 1.57e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs12088486 — 0.56 1.75e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10959258 — 1.36 1.86e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs7622678 BDH1 — 1.93e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs4720752 RPA3 — 1.93e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs6769400 — 1.91 1.99e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6689491 — — 2e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs6962026 PSCD3 — 2.07e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs9595687 — 0.49 2.09e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs11237644 — 1.52 2.11e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs4938180 IGSF4 1.91 2.16e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2147556 — 0.63 2.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10493515 — — 2.3e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs1563301 — 0.50 2.36e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10901296 ABL1 — 2.37e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs6592810 — 1.54 2.49e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs680109 GRIA4 — 2.52e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C A Genome-Wide Association Study 22445811
    rs1537438 — — 2.53e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs11206814 — — 2.67e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs571391 IMPG2 0.55 2.67e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs12562047 UCK2 — 2.7e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A C Genome-Wide Association Study 22445811
    rs3803833 — 0.77 2.72e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs2710548 FAT4 — 2.79e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs7915479 CDH23 1.92 2.81e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue