Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    No Age Effect « 
  • Study type: + -
    Candidate Region/Gene « 
  • Variant type: + -
    SNP (63)  
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs2494732 AKT1 1.04 0.406 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs17881426 SOD3 — 0.425 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs8192290 SOD3 — 0.428 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2494748 AKT1 0.95 0.466 1383 vs 736 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs5746133 SOD2 — 0.466 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2494731 AKT1 1.03 0.503 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs17630266 FOXO1 1.11 0.51 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs4998557 SOD1 — 0.52 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs11585393 FOXO6 1.04 0.531 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs1130214 AKT1 0.97 0.544 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs3803304 AKT1 0.97 0.544 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs4880 SOD2 — 0.552 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs1078892 FOXO1 0.96 0.589 1447 vs 1029 (German) 166 vs 216 (Italian) German — — — Candidate Region/Gene 21388494
    rs2951787 FOXO1 1.03 0.6 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs5746141 SOD2 — 0.601 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs4986790 TLR4 — 0.61 273 vs 594 — German Mean age 97.9 — — Candidate Region/Gene 17493663
    rs699473 SOD3 — 0.613 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2755213 FOXO1 0.95 0.626 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs4660192 FOXO6 0.97 0.663 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs1007991 SOD3 — 0.679 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2842980 SOD2 — 0.689 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs12013673 FOXO4 0.98 0.696 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs2494738 AKT1 1.03 0.718 2996 vs 1840 — Danish, German 92-110 — — Candidate Region/Gene 22929028
    rs7539614 FOXO6 1.02 0.739 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs6917589 SOD2 — 0.741 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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