Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

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  • Variant effect: + -
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    Candidate Region/Gene (17)   Meta‑Analysis (1)   Mitochondrial Haplogroup (25)  
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    Haplotype « 
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    9bp-deletion,10873T mtDNA — 0.311 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    8584A,9bp-deletion,10873T mtDNA — 0.117 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    15235G,8584A,9bp-deletion,10873T mtDNA — 0.086 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    15662G,8584A,9bp-deletion,10873T mtDNA — 0.357 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    5465C,9bp-deletion,10873T mtDNA — 0.105 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    13590A,9bp-deletion,10873T mtDNA — 0.43 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    rs3176343-rs3176344-rs3176349-rs1801270 CDKN1A — 0.9852 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs3176343-rs3176344-rs3176349-rs1801270 CDKN1A — 0.1761 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs3176343-rs3176344-rs3176349-rs1801270 CDKN1A — 0.1282 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 CDKN1A — 0.8 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 CDKN1A — 0.1856 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs3176343-rs3176344-rs3176349-rs1801270-rs1059234-rs876581 CDKN1A — 0.139 184 vs 184 — Italian 100 — — Candidate Region/Gene 20126416
    rs1800591-rs61733139 MTTP — 0.93 164 vs 261 — Dutch Mean age 93.8 ± 3.1 — — Candidate Region/Gene 16611701
    rs11279109 - SI000565Q APOB — 0.05 191 (case) vs 53 — Chinese > 90 baseline, Mean age 97 +/- 3 D - S D - M Candidate Region/Gene 17393087
    rs11279109 - APOB XbaI APOB — 0.001 191 (case) vs 53 (initial) — Chinese > 90 baseline, Mean age 97 +/- 3 — D - X+ Candidate Region/Gene 17393087
    rs11279109 - APOB XbaI - SI000565Q APOB — 0.044 191 (case) vs 53 — Chinese > 90 baseline, Mean age 97 +/- 3 D - X+ - Short I - X+ - Medium; D - X- - Long; D - X- - Medium Candidate Region/Gene 17393087
    rs1800796-(−373(A)n(T)m)-rs1800795 IL6 — 0.07 1710 total — Danish 47-100 G-(−373(A)8(T)12)-C non G-(−373(A)8(T)12)-C haplotypes Candidate Region/Gene 15130757
    APOB XbaI − SI000565Q APOB — 0.006 191 (case) vs 53 (initial) — Chinese > 90 baseline, Mean age 97 +/- 3 X+ - Short X+ - Medium Candidate Region/Gene 17393087

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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