Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated « 
  • Study type: + -
    GWAS (2)   ‑ (1)   Candidate Region/Gene (153)   Meta‑Analysis (30)   Genome‑Wide Association Study (50)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP « 
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579
    rs4073591 DEAF1 — 0.002618 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
    rs4073590 DEAF1 — 0.004259 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
    rs4930001 DEAF1 — 0.010851 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
    rs800140 TSPAN32 — 0.0081 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
    rs16928120 — — 0.00057 1600 samples (cases and controls combined) — German, Italian — — — Candidate Region/Gene 19367319
    rs1061170 CFH 1.78 0.005 491 vs 0 — Finn — His — — 19000922
    rs3772190 TERC — 0.006 1013 total — Danish — A G Candidate Region/Gene 22136229
    rs4673 — 1.48 0.022 — — Russian — C T Candidate Region/Gene 23755540
    rs1801270 CDKN1A 0.44 0.02 184 vs 184 — Italian 100 A C Candidate Region/Gene 20126416
    rs1059234 CDKN1A 0.47 0.026 184 vs 184 — Italian 100 T C Candidate Region/Gene 20126416
    rs2075650 APOE 0.53 4.44e-16 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1525501 — 0.72 4.94e-06 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs3803833 — 0.77 2.72e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1016013 — 1.21 2.87e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs216148 CSF1R 0.75 6.36e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1867102 C9orf3 1.20 7.28e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1822590 — 1.21 7.57e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs4918255 SORCS1 1.21 8.81e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1456669 — 0.78 9.89e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs915179 LMNA 1.19 0.0001 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs2738679 WWOX 1.60 6.85e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs17702471 GPC6 1.81 8.33e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1042663 C2 0.72 8.39e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs651922 DCPS 1.65 0.00018 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    • Page 1 of 10
    • 25 of 243 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue