GSTT1

Symbol: GSTT1
Name: glutathione S-transferase theta 1
Entrez gene ID: 2952
Ensembl gene ID: ENSG00000184674
Species: Human (Taxid: 9606)


Observation:

Deletion in the GSTT1 was examined in 94 nonagenarians and centenarians and 418 control subjects of younger age. A significant difference in the proportion of nonagenarians and centenarians homozygotes for the deletion was observed in comparison to control subjects [11162685].GSTT1 was found to be associated with longevity [11162685]. GSTT1 was found to be associated with longevity [16574194]. GSTT1 was not found to be associated with longevity [11162685]. GSTT1 was not found to be associated with longevity [15195682].



Assays: Organismal Lifespan

Longevity Associated Variants:
  • GSTT1 gene deletion 0.001 [16574194]
  • Presence/Deletion 0.2 [15195682]
  • GSTT1 deletion 0.03 [11162685]

  • Classification:
  • Longevity-Associated
  • No Age Effect


  • Type:
  • Gene
  • Protein coding

    References:
  • 11162685: Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus.


  • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

  • Homologs
  • GSTT1 (9606)
  • GSTT1 (9598)
  • GSTT1 (9615)
  • GSTT1 (9913)
  • Gstt1 (10090)
  • Gstt1 (10116)
  • GSTT1 (9031)
  • GSTT1 (9031)
  • gstt1b (7955)
  • gstt1a (7955)
  • CG1681 (7227)

  • Inparanoids
  • ENSMUSP00000001713 (10090)
  • ENSRNOP00000001666 (10116)
  • ENSMMUP00000041010 (9544)
  • ENSP00000248935 (9606)



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