Denigma Buck Institute Health Extension
Polymorphism: GSTT1 deletion



Location: 22q11.23

Factor:
- Symbol: GSTT1
- Name: glutathione S-transferase theta 1
- Entrez ID: 2952
- Ensembl ID: ENSG00000184674

Factors:
  • GSTT1 glutathione S-transferase theta 1 ( 2952 / ENSG00000184674 )


    • Description:

    Candidate gene

    Ethnicity: Italian
    Age of cases: Mean age 100.2
    Shorter lived allele: Not homozygous for d
    Longer lived allele: Homozygous for delet

    Statistics
    - Number of cases/controls: 94 vs 418 (initial)
    - p-value: 0.03
    - Significant: Yes

    Study Design
    - Classifications: Longevity-Associated
    - Study type: Candidate Region/Gene
    - Technology: Multiplex PCR

    Reference:
    11162685: Polymorphisms of drug-metabolizing enzymes in healthy nonagenarians and centenarians: difference at GSTT1 locus.

    Choice: Curate_Johnny
    Created: July 1, 2013, 12:06 a.m.
    Updated: Aug. 8, 2014, 1:05 p.m.

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