Denigma cartographies changes from the molecular level to whole physiology which occur in defined contrasts such as aging and dietary as well as genetic lifespan-extending interventions:
| ID | name | taxid | reference | pmid | tissue | comparision | start | stop | gender | description |
|---|---|---|---|---|---|---|---|---|---|---|
| 121 | Smaller body size | 6239 | — | 22810224 | — | mutation | eat-2 | wild-type | — | eat-2 mutants are noticeable smaller than wild-type [22810224]. |
| 4 | HDL decrease | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 5 | HDL increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 7 | VLDL decrease | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 8 | VLDL decrease | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 10 | LDL decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 11 | Valine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 12 | Isoleucine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 13 | Lactate decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 14 | 2-hydroxyisobutyrate increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 15 | Acetate decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 17 | N-acetyl glycoprotein increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 18 | N-acetyl glycoprotein increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 19 | Methionine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 20 | Methionine increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 23 | D-3-hydroxybutyrate increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 25 | Citrate increases | 10099 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 27 | Trimethylamine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 28 | Trimethylamine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 31 | Glycerophosphocholine decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 32 | Glycerophosphocholine increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1df/df at 16 weeks | — | male | — |
| 34 | Scyllo-inositol increases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Mutant | Irs1-/- at 16 weeks | — | male | — |
| 3 | HDL decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Diet | 30% DR for 48h at 16 weeks | — | male | — |
| 6 | VLDL decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Diet | 30% DR for 48h at 16 weeks | — | male | — |
| 9 | LDL decreases | 10090 | Wijeyesekera et al., 2012 | 22225495 | Plasma | Diet | 30% DR for 48h at 16 weeks | — | male | — |
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