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Denigma
»
Lifespan
»
Variants
» Variant = mtDNA haplogroups
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Mouse Lifespan Experiments
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mtDNA haplogroups
Polymorphism:
mtDNA haplogroups
Variant Type:
Haplotype
Location:
1q32
Factor:
- Symbol:
mtDNA
- Name:
renin
- Entrez ID:
5972
- Ensembl ID:
ENSG00000143839
Factors:
mtDNA
renin
(
5972
/
ENSG00000143839
)
Description:
Successful agers over 80 vs others overs 80
Ethnicity:
Amish
Age of cases:
>80 years
Shorter lived allele:
J
Longer lived allele:
non-J
Finding:
Positive
Statistics
- Number of cases/controls:
74 vs 187 (initial)
- Odds ratio:
0.4
- p-value:
0.0003 [0.0003]
- Significant:
Yes
Study Design
- Classifications:
Longevity-Associated
- Study type:
Mitochondrial Haplogroup
- Technology:
Affymetrix 6.0 GeneChip Human Mapping 1 million SNP array set
Reference:
21750925: Mitochondrial haplogroup X is associated with successful aging in the Amish.
Choice:
Curate_Jimi
Created:
July 1, 2013, 12:56 p.m.
Updated:
Aug. 8, 2014, 1:06 p.m.
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