Polymorphism: mtDNA haplogroups
Variant Type: Haplotype
Location: 1q32
Factor:
- Symbol: mtDNA
- Name: renin
- Entrez ID: 5972
- Ensembl ID: ENSG00000143839
Factors:
mtDNA
renin
(
5972
/
ENSG00000143839
)
Description:
Successful agers over 80 vs others overs 80
Ethnicity:
Amish
Age of cases: >80 years
Shorter lived allele: J
Longer lived allele: non-J
Finding: Positive
Statistics
- Number of cases/controls: 74 vs 187 (initial)
- Odds ratio: 0.4
- p-value:
0.0003
[0.0003]
- Significant: Yes
Study Design
- Classifications:
Longevity-Associated
- Study type: Mitochondrial Haplogroup
- Technology: Affymetrix 6.0 GeneChip Human Mapping 1 million SNP array set
Reference:
21750925: Mitochondrial haplogroup X is associated with successful aging in the Amish.
Choice: Curate_Jimi
Created: July 1, 2013, 12:56 p.m.
Updated: Aug. 8, 2014, 1:06 p.m.
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