Denigma Buck Institute Health Extension

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polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
e4 APOE — 0.04 376 vs 376 — Canadian 85+ e4 — Candidate Region/Gene 24126160
rs12978931 PVRL2 1.15 0.0445 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs519825 PVRL2 1.28 0.01577 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs419010 PVRL2 1.13 0.091 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs4803766 PVRL2 0.97 0.708 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs11879589 PVRL2 1.67 0.07601 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs395908 PVRL2 0.81 0.048 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs519113 PVRL2 0.90 0.3734 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs6857 PVRL2 0.90 0.518 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs10119 TOMM40 0.94 0.914 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs449647 APOE 1.01 0.767 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs405509 APOE 1.18 0.027 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs440446 APOE 1083.00 0.509 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs769448 APOE 1.09 0.66 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs769449 APOE 0.90 0.62 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs7412 APOE 1.15 0.405 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs429538 APOE 0.88 0.2821 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs4420638 — 0.85 0.176 597 vs 1275 — Sichuan 90+ — — Candidate Region/Gene 24924924
rs2075650 TOMM40 1.43 0.006 597 vs 1275 418 vs 450 Sichuan 90+ — — Candidate Region/Gene 24924924
rs7843014 — 0.37 0.001 175 vs 355 — Spanish 100-111 A C Candidate Region/Gene 24930376
rs7460 PTK2 0.40 0.001 175 vs 355 — Spanish 100-111 A T Candidate Region/Gene 24930376
e4 APOE 0.55 0.03 163 vs 1039 — Spanish 100+ e4 — Candidate Region/Gene 24534555
rs1333049 CDKN2B-AS1 — 0.088 152 vs 343 — Spanish 100 C G Candidate Region/Gene 24163049
rs2802292 FOXO3A 1.36 0.005 2521 vs 2537 — Multiethnic 90+ — — Meta-Analysis 25038186
rs2764264 FOXO3A 1.20 0.01 1959 vs 1621 — Multiethnic 90+ — — Meta-Analysis 25038186
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  • 25 of 1635 variants