Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    No Age Effect (33)  
  • Study type: + -
    Candidate Region/Gene (33)  
  • Variant type: + -
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs6589722 — — 0.015 209 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs3745548 INSR — 0.057 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs17356414 JUN — 0.082 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs2252673 INSR — 0.083 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs12786104 CBL — 0.12 210 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs10811661 — — 0.13 213 vs 402 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs3779501 PIK3CG — 0.139 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2511837 CBL — 0.14 212 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs1776180 EXO1 — 0.16 206 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs3745546 INSR — 0.168 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs1815274 JUN — 0.18 212 vs 401 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs1799817 INSR — 0.205 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2288404 INSR — 0.277 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2999131 — — 0.31 208 vs 391 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs1801278 IRS1 — 0.337 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2305268 PIK3CB — 0.363 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs6519194 ATF4 — 0.41 206 vs 397 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs3745544 INSR — 0.441 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs8192678 PPARGC1A — 0.469 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2297627 FOXO1A — 0.495 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs3736265 PPARGC1A — 0.509 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs2297626 FOXO1A — 0.512 122 vs 122 — Japanese mean age 106.8 — — Candidate Region/Gene 15582274
    rs1853432 JUN — 0.52 213 vs 398 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs738288 ATF4 — 0.54 205 vs 396 — Japanese 95+ — — Candidate Region/Gene 23770741
    rs1333049 CDKN2B-AS1 — 0.602 742 vs 920 — Japanese 100 — — Candidate Region/Gene 24163049
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    • 25 of 33 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue