Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (30)   No Age Effect (8)  
  • Study type: + -
    Meta‑Analysis « 
  • Variant type: + -
    SNP (37)   Haplotype (1)  
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs7762395 FOXO3A — 1.0 2832 vs 2168 — Multiethnic 90+ — — Meta-Analysis 25038186
    rs13220810 FOXO3A — 1.0 1746 vs 1219 — Multiethnic 90+ — — Meta-Analysis 25038186
    rs651922 DCPS 1.65 0.00018 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs2738173 DEFB1 0.78 0.00016 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs17702471 GPC6 1.81 8.33e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs216148 CSF1R 0.75 6.36e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1042663 C2 0.72 8.39e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs1867102 C9orf3 1.20 7.28e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs11954180 SLC6A7 1.30 0.001639 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
    rs4918255 SORCS1 1.21 8.81e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs2596230 RYR3 2.61 0.000383 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
    rs4729049 CDK6 1.21 0.001311 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
    rs2738679 WWOX 1.60 6.85e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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