Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    No Age Effect « 
  • Study type: + -
    Candidate Region/Gene « 
  • Variant type: + -
    SNP (63)  
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    Populations | Study Types | Variant Types


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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs2071069 TPI1 — 0.05 1422 vs 967 — German mean age: 98.8, age range: 95–110 (SNP is G/A) — Candidate Region/Gene 18510744
    rs2071065 TPI1 — 0.05 1422 vs 967 — German mean age: 98.8, age range: 95–110 (SNP is T/C) — Candidate Region/Gene 18510744
    rs1801274 FCGR2A — 0.05 408 vs 446 vs 454 — German 100–110/ mean101.3 (SNP is His/Arg) — Candidate Region/Gene 16893392
    rs2721044 FOXO1 0.90 0.097 1447 vs 1029 (German) 166 vs 216 (Italian) German — — — Candidate Region/Gene 21388494
    rs662 PON1 1.06 0.11 — — Danish, Dutch, French, German, Italian, Tatar >/=80 — — Candidate Region/Gene 20362697
    rs2701859 FOXO1 0.90 0.117 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs2701880 FOXO1 0.83 0.12 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs11581271 FOXO6 0.91 0.131 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs8192291 SOD3 — 0.144 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs2721047 FOXO1A 0.98 0.177 1447 vs 1029 (initial) 166 vs 216 (Italian) (replication) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs2984121 FOXO1 1.05 0.178 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs8031 SOD2 — 0.186 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    rs7547654 FOXO6 1.08 0.2 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs4660532 FOXO6 0.93 0.224 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs1986649 FOXO1 0.92 0.229 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs2721069 FOXO1 0.93 0.251 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs1317558 FOXO6 1.11 0.257 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs2866164 MTTP 1.21 0.28 373 vs 540 1033 vs 359 German Centenarians G C Candidate Region/Gene 15911777
    rs12865518 FOXO1 1.07 0.307 1447 vs 1029 (German) 166 vs 216 (Italian) German — — — Candidate Region/Gene 21388494
    rs4943794 FOXO1 0.93 0.313 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs11209971 FOXO6 0.94 0.336 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs17446593 FOXO1 0.93 0.338 1447 vs 1029 (German) 166 vs 216 (Italian) German — — — Candidate Region/Gene 21388494
    rs2866164 MTTP 1.18 0.34 666 vs 540 1033 vs 359 German <100 G C Candidate Region/Gene 15911777
    rs7981045 FOXO1 1.06 0.349 1447 vs 1029 (German) 166 vs 216 (Italian) German Mean age 98.8 — — Candidate Region/Gene 21388494
    rs5746136 SOD2 — 0.354 1612 vs 1104 — German 90+ — — Candidate Region/Gene 24163049
    • Page 1 of 3
    • 25 of 73 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue