Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (607)   No Age Effect (103)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (147)   Locus (1)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
    Export results (Download)

    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
    logo.png
    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs1002098 Intergenic 1.25 0.000996526 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
    rs1005321 HS3ST3B1 1.17 0.000337804 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs10055012 SEMA6A 1.20 0.001722103 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
    rs10062090 Intergenic 0.69 2.85e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs10084768 Intergenic 1.15 0.000217915 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs10124818 Intergenic 0.92 7.73e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs10134056 — 0.46 5.61e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10140519 Intergenic 1.49 0.000397649 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1016013 Intergenic 1.30 3.61e-05 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1016339 Intergenic 1.42 0.000102714 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs10190125 MYT1L 1.24 0.000168452 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs10191593 Intergenic (downstream of SSBP3 and MRPL37) 1.49 6.97e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — A Genome-Wide Association Study 21418511
    rs10194564 Intergenic (upstream of LRP1B) 1.55 8.88e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — A Genome-Wide Association Study 21418511
    rs10202497 Intergenic 0.89 8.22e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs10210870 Intergenic 1.27 0.001298236 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs10211241 Intergenic 1.07 7.62e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — T — Genome-Wide Association Study 21782286
    rs10229977 Intergenic 1.86 0.001130238 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs10256177 Intergenic 1.16 8.81e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — A — Genome-Wide Association Study 21782286
    rs10256972 C7orf50 — 0.00224 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs10259086 Intergenic 1.08 5.16e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — T — Genome-Wide Association Study 21782286
    rs10263457 Intergenic 1.11 0.001203582 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs10277343 — 0.64 3.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1033686 RAD51L1 1.30 0.002359037 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs10401068 DOK6 1.36 9.62e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — A Genome-Wide Association Study 21418511
    rs10412199 ATCAY 0.91 3.02e-06 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue