Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (607)   No Age Effect (103)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (147)   Locus (1)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs739401 CARS — 0.00154 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs10256972 C7orf50 — 0.00224 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs10937739 PPP2R2C — 0.00404 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs5771675 FAM19A5 — 0.00985 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs12623542 Noncoding — 0.00192 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
    rs9616906 AC000050.2 — 9.36e-05 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs13053175 RAC2 — 0.00697 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs4148544 ABCC4 — 0.00977 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs2370413 CACNA1C — 0.0011 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs10819510 Intergenic — 0.00774 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs1205035 Intergenic — 0.00983 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs432203 TGFA — 0.00779 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs1327533 SVEP1 — 0.000356 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
    rs2826891 NCAM2 — 0.00402 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    Q/H 95, rs2866164 — — 0.0005 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Q95 G — Genome-Wide Association Study 14615589
    rs752766 Intergenic — 0.0058 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 — — Genome-Wide Association Study 14615589
    rs951085 Intergenic — 0.0041 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 — — Genome-Wide Association Study 14615589
    rs750032 PPP3CA — 0.0029 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 — — Genome-Wide Association Study 14615589
    rs1553432 Intergenic (upstream of C4orf17) — 0.0005 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 — — Genome-Wide Association Study 14615589
    rs987839 SLCO1B1 — 3.19e-06 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs17205854 — — 3.74e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs17811551 ADAMTS6 — 3.74e-06 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs1857821 NAAA — 5.12e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs7525717 — — 5.76e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs4673651 ERBB4 — 6.08e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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