Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (50)   No Age Effect (97)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP « 
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs970048 Intergenic 1.77 7.17e-07 3746 vs 5912 — Dutch Mean age 94 — G Genome-Wide Association Study 21418511
    rs969845 — 5.87 7.22e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs964403 SUMF1 2.07 4.91e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs9595687 — 0.49 2.09e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs9366292 — 0.64 8.65e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs9330200 TUBB4B — 6e-53 5036 — American 28-70 AA, AT TT Genome-Wide Association Study 22174011
    rs9315385 DCAMKL1 1.74 8.13e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs888808 RHOBTB3 0.67 4.19e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs870959 — 1.51 2.84e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs846427 — 1.94 3.82e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs81647 — 0.58 9.77e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs795602 MGST2 0.67 4.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs7915479 CDH23 1.92 2.81e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs7873259 ANKRD19 3.14 1.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs7842001 — 0.32 7.12e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs7583529 CFLAR 3.15 6.45e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs731287 — 2.51 9.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs712773 GRM7 0.66 9.99e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs697739 ATXN1 0.59 8.97e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6769400 — 1.91 1.99e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6701445 TAF5L 1.84 4.19e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6689491 — — 2e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs6657082 — — 5.5e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs6592810 — 1.54 2.49e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs6540664 — 1.46 9e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    • Page 1 of 6
    • 25 of 147 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue