Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (607)   No Age Effect (103)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (147)   Locus (1)  
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    Populations | Study Types | Variant Types


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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs9997032 Intergenic 0.93 3.46e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs999228 Intergenic 0.94 4.17e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs9977638 BTG3 1.30 0.000185861 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs997675 Intergenic 1.24 1.41e-05 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs9944366 Intergenic 1.09 2.93e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — C — Genome-Wide Association Study 21782286
    rs9916344 PITPNM3 1.19 0.000353663 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs9899404 GIP 1.30 1.09e-05 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs9898180 Intergenic 1.14 9.56e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — A — Genome-Wide Association Study 21782286
    rs9894254 CARD14 1.77 0.000864702 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs9889219 Intergenic 1.08 2.39e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — A — Genome-Wide Association Study 21782286
    rs9876781 Noncoding — 0.000868 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs9868286 CCDC50 1.48 7.4e-06 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — C Genome-Wide Association Study 21418511
    rs982764 FAS 1.10 0.000335327 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs9827142 Intergenic 1.49 4.88e-06 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — C Genome-Wide Association Study 21418511
    rs9811637 Intergenic 0.94 8.83e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — T Genome-Wide Association Study 21782286
    rs975072 Intergenic 1.24 0.000318229 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs970567 Intergenic 0.70 3.5e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 C — Genome-Wide Association Study 21418511
    rs970048 Intergenic 1.77 7.17e-07 3746 vs 5912 — Dutch Mean age 94 — G Genome-Wide Association Study 21418511
    rs970048 Intergenic 1.77 7.17e-07 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — G Genome-Wide Association Study 21418511
    rs969845 — 5.87 7.22e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs9662589 Intergenic 1.43 9.68e-05 403 vs 1670 3746 vs 5912 Dutch Mean age 94 — C Genome-Wide Association Study 21418511
    rs9657161 Intergenic 0.93 1.55e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs9652250 Intergenic 1.46 0.00021962 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs9646894 Intergenic 0.73 7.64e-05 5974 (RS), 3267 (CHS), 3136 (FHS), 4511 (ARIC), 3219 (AGES), 902 (inCHIANTI), 620 (BLSA), 1661 (HABC), 1717 (SHIP) Whitehall II - 6000 (UK), English Longitudinal Study of Ageing (UK), Religious Order Study - 1100, Memory and Ageing Project American — — A Genome-Wide Association Study 21782286
    rs964403 SUMF1 2.07 4.91e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    • Page 1 of 29
    • 25 of 710 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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