Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated « 
  • Study type: + -
    Meta‑Analysis « 
  • Variant type: + -
    SNP (30)  
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    Populations | Study Types | Variant Types


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    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs4729049 CDK6 1.21 0.001311 2715 vs 2725 — Multiethnic 100 — — Meta-Analysis 24244950
    rs4918255 SORCS1 1.21 8.81e-05 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs651922 DCPS 1.65 0.00018 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs915179 LMNA 1.19 0.0001 2202 vs 2164 — Caucasian 100 — — Meta-Analysis 24244950
    rs9536314 KL 1.14 0.05 2913 vs 2206 — Multiethnic — — — Meta-Analysis 24164579

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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