Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
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  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (97)  
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs135416 — 0.57 8.65e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1405051 — — 0.00014 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs1428689 — 1.85 5.51e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1484583 — 1.53 7.66e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1528753 — — 8.1e-08 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs1538287 KCNH1 0.55 4.87e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1556758 SORCS1 0.50 3.47e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1562688 — 0.50 4.93e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1563301 — 0.50 2.36e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1575892 — 0.45 9.32e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs1582594 — 1.87 4.76e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1584547 — 2.96 8.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs158869 — 1.37 4.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs1610601 — 0.68 1.98e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs1610742 — 0.66 3.02e-07 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs1633063 — 0.68 3.82e-06 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs16947526 — 0.56 1.23e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs1800802 MGP 0.77 0.132 137 vs 213 — Korean Mean age 90 C — Genome-Wide Association Study 19641380
    rs1915501 — — 0.00011 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs2070325 LPLUNC4 2.42 5.98e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2073586 ABCC8 0.48 8.15e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2111173 PTPRO 1.74 9.24e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2147556 — 0.63 2.18e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs2274471 JAK2 (for males) 1.58 0.088 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
    rs2277472 MAMDC1 1.95 7.93e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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