Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

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    SNP (97)  
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    (rs429358, rs7412) + (rs2075650) APOE + TOMM40 0.93 0.337 403 vs 1670 3746 vs 5912 Dutch Mean age 94 e4 + G — Genome-Wide Association Study 21418511
    3p24.2–22.3 — — 0.037 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
    9q31.3–34.2 — — 0.054 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
    rs10134056 — 0.46 5.61e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10277343 — 0.64 3.88e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10489006 — — 3.6e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10493513 — — 1.5e-06 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10493514 — — 2.8e-06 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10493515 — — 2.3e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10493517 — — 4.2e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10493518 — — 3.6e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10496799 NXPH2 — 1.4e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10498263 OR4Q3 — 8.3e-05 1345 cohort + 1087 offspring — American — — — Genome-Wide Association Study 17903295
    rs10513702 — 1.85 4.53e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10514626 — 0.38 1.12e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs1054016 TNFSF11 1.09 0.579 137 vs 213 — Korean Mean age 90 T — Genome-Wide Association Study 19641380
    rs10923806 — 2.30 7.24e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10956502 FAM49B 0.57 4.21e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs10959258 — 1.36 1.86e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs11237644 — 1.52 2.11e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs11738302 — 0.57 6.89e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs11790055 — 1.38 1.49e-05 763 vs 1085 754 vs 850 German Mean age 99.7 — — Genome-Wide Association Study 21740922
    rs12088486 — 0.56 1.75e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs12413082 MSRB2 0.53 3.33e-06 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    rs130329 — 0.50 3.52e-05 410 vs 553 — Italian 90–109 — — Genome-Wide Association Study 21612516
    • Page 1 of 5
    • 25 of 103 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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