Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

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    ‑ (19)   Candidate Region/Gene (382)   Meta‑Analysis (8)   Genome‑Wide Association Study (103)   Mitochondrial Haplogroup (27)  
  • Variant type: + -
    SNP (314)   Haplotype (43)   Other (1)   STR (7)   Deletion (1)  
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    -670A/G FAS — 0.608 50 vs 86 — Italian 100.8 ± 1.8 (100 to 106) — — Candidate Region/Gene 11965496
    10646A,10400T mtDNA — 0.753 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    11 different snps tested, not all given. MTTP — 1.0 1398 vs 777 — British 77.9 ± 0.2 — — Candidate Region/Gene 17339647
    1107C,5178A,10400T mtDNA — 0.559 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    12406A,3970T,12705C,10873T mtDNA — 0.304 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    12811C,9824C,10400T mtDNA — 0.587 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    13263G,7196A,10400T mtDNA — 0.485 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    13590A,9bp-deletion,10873T mtDNA — 0.43 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    14569A,10400T mtDNA — 0.796 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    14979C,3010A,5178A,10400T mtDNA — 0.781 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    15235G,8584A,9bp-deletion,10873T mtDNA — 0.086 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    15662G,8584A,9bp-deletion,10873T mtDNA — 0.357 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    16 bp duplication in intron 3 (WT=no duplicaiton) TP53 — 0.59 66 vs 150 — Italian 100.19±2.2 (95-105) — — Candidate Region/Gene 15195682
    1736G,10873T mtDNA — 0.288 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    3'APOB-VNTR APOB — 0.29 175 vs 200 — Danish >100 — — Candidate Region/Gene 11592926
    3010A,5178A,10400T mtDNA — 0.141 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    3970T,12705C,10873T mtDNA — 0.147 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    3p24.2–22.3 — — 0.037 632 (total) — Caucasian By Expected age of death: Male 90-100, Female 95-104 — — Genome-Wide Association Study 20824210
    4833G,14569A,10400T mtDNA — 0.949 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    5178 adenine/cytosine ND2 — 0.363 95 vs 298 — Chinese 76.2±5.0 C — Candidate Region/Gene 12384792
    5178A,10400T mtDNA — 0.387 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    5465C,9bp-deletion,10873T mtDNA — 0.105 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    7196A,10400T mtDNA — 0.847 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    7600A,4833G,14569A,10400T mtDNA — 0.153 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    8020A,3010A,5178A,10400T mtDNA — 0.549 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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