Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated « 
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (50)   Locus (1)  
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    Populations | Study Types | Variant Types


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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    marker D4S1564 — — 0.044 308 — European min. age 98 for one sibling. 91+ males, 95+ females — — Genome-Wide Association Study 11526246
    rs3811952, rs155979, rs3762985 — 0.54 0.008 137 vs 213 — Korean Mean age 90 CGA — Genome-Wide Association Study 19641380
    rs712700 — 1.87 0.01 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
    rs327512 — 5.55 0.005 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
    rs1979128 — 2.10 0.006 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
    rs1450740, rs1450741, rs1562818, rs1980042, rs1027989, rs 1546518, rs3968371 — 3.72 0.002 137 vs 213 — Korean Mean age 90 — CTCCGCA Genome-Wide Association Study 19641380
    Q/H 95, rs2866164 — — 0.0005 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 Q95 G — Genome-Wide Association Study 14615589
    rs17205854 — — 3.74e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs7525717 — — 5.76e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs17049647 — — 7.12e-06 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs1418425 — — 9.64e-06 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs1537438 — — 2.53e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G T Genome-Wide Association Study 22445811
    rs11206814 — — 2.67e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs6454676 — — 2.9e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs10485170 — — 3.67e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs3125524 — — 3.83e-05 1364 — American, British Age range 50-108; mean age at death 80.2 C T Genome-Wide Association Study 22445811
    rs4280854 — — 3.85e-05 1364 — American, British Age range 50-108; mean age at death 80.2 A G Genome-Wide Association Study 22445811
    rs1037381 — — 3.99e-05 1364 — American, British Age range 50-108; mean age at death 80.2 G A Genome-Wide Association Study 22445811
    rs6491207 — — 4.63e-05 1364 — American, British Age range 50-108; mean age at death 80.2 T C Genome-Wide Association Study 22445811
    rs2075650 APOE 0.71 3.39e-17 403 vs 1670 4149 vs 7582 Dutch mean 94 e4 — Genome-Wide Association Study 21418511
    rs4420638 APOE — 9.6e-08 4445 total (each a part of sibship of 2-5 siblings) — Caucasian, European 90 — — Genome-Wide Association Study 23286790
    rs915179 LMNA 1.34 2.3666e-05 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs2963154 NR3C1 1.10 0.0010712 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs3019435 PARK2 1.41 0.001006354 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
    rs1800392 WRN 1.19 0.000178635 801 vs 914 — Caucasian Median age 104 C A Genome-Wide Association Study 22279548
    • Page 1 of 25
    • 25 of 607 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue