Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (40)   No Age Effect (60)  
  • Study type: + -
    ‑ (3)   Candidate Region/Gene (70)   Complete Mitochondrial Genome (1)   Mitochondrial Haplogroup (30)  
  • Variant type: + -
    SNP (31)   Locus (2)   Haplotype (40)   STR (5)   Deletion (1)  
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    C150T mtDNA L2 — 1.0 556 vs. 403 — Chinese 90-108 — — Mitochondrial Haplogroup 21262335
    5178 adenine/cytosine ND2 — 0.363 95 vs 298 — Chinese 76.2±5.0 C — Candidate Region/Gene 12384792
    MTP -493G/T MTP — 0.854 — — Chinese — — — - 23273182
    rs4746720 — 1.35 0.022 246 vs 236 — Chinese 60-90 — C Candidate Region/Gene 20633545
    rs4646994 ACE — 0.05 4000 — Chinese Minimum age 65 DD — Candidate Region/Gene 22456784
    mt5178A ND2 — 0.05 95 vs 105 — Chinese Mean age 76 — АА Candidate Region/Gene 12384792
    rs189037 (genotype) ATM — 0.004 875 (280 m, 595 f) vs 886 (491 m, 395 f) — Chinese Mean age 94,6, healthy — CT (Article); GA (ENSEMBL) Candidate Region/Gene 20816691
    VNTR DC-SIGNR — 0.041 361 vs 342 — Chinese >90 non-6/7 genotype 6/7 genotype Candidate Region/Gene 20003397
    5178A,10400T mtDNA — 0.387 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    3010A,5178A,10400T mtDNA — 0.141 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    14979C,3010A,5178A,10400T mtDNA — 0.781 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    8020A,3010A,5178A,10400T mtDNA — 0.549 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    8964T,8020A,3010A,5178A,10400T mtDNA — 0.319 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    9296T,8964T,8020A,3010A,5178A,10400T mtDNA — 0.55 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    1107C,5178A,10400T mtDNA — 0.559 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    14569A,10400T mtDNA — 0.796 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    4833G,14569A,10400T mtDNA — 0.949 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    7600A,4833G,14569A,10400T mtDNA — 0.153 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    9824C,10400T mtDNA — 0.955 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    12811C,9824C,10400T mtDNA — 0.587 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    7196A,10400T mtDNA — 0.847 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    8684T,7196A,10400T mtDNA — 0.457 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    13263G,7196A,10400T mtDNA — 0.485 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    4491A,3705G,10400T mtDNA — 0.027 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    10646A,10400T mtDNA — 0.753 463 vs 1389 — Chinese >/=95 — — Mitochondrial Haplogroup 19641616
    • Page 1 of 5
    • 25 of 104 variants

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

    Suggest a new study Report a database issue