Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (607)   No Age Effect (103)  
  • Study type: + -
    Genome‑Wide Association Study « 
  • Variant type: + -
    SNP (147)   Locus (1)  
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    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs3120819 Intergenic — 0.00806 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs3811952, rs155979, rs3762985 — 0.54 0.008 137 vs 213 — Korean Mean age 90 CGA — Genome-Wide Association Study 19641380
    rs2030071 IL12RB2 (for females) 0.18 0.008 137 vs 213 — Korean Mean age 90 T — Genome-Wide Association Study 19641380
    rs12129750 VPS13D 1.06 0.007897685 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs432203 TGFA — 0.00779 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs10819510 Intergenic — 0.00774 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs2043270 FLJ31951 1.29 0.00761736 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs16975963 Noncoding — 0.00713 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
    rs13053175 RAC2 — 0.00697 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs13008689 Intergenic — 0.00686 1173 vs 570 — American 85-100 — A Genome-Wide Association Study 22533364
    rs4497194 Intergenic 1.26 0.006460551 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1980042 LYN (for males) 2.10 0.006 137 vs 213 — Korean Mean age 90 — C Genome-Wide Association Study 19641380
    rs1979128 — 2.10 0.006 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
    rs752766 Intergenic — 0.0058 653 (197 m, 456 f) vs non-mentioned 564 (92 m, 472 f) vs 564___(Franch Caucasians) American, Caucasian Mean 100,8 — — Genome-Wide Association Study 14615589
    rs2312243 Intergenic 1.09 0.005424222 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs3800358 BTBD9 — 0.00541 1173 vs 570 — American 85-100 — T Genome-Wide Association Study 22533364
    rs8003961 DLG7 1.10 0.005011434 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs327512 — 5.55 0.005 137 vs 213 — Korean Mean age 90 — G Genome-Wide Association Study 19641380
    rs1974676 Intergenic — 0.00496 1173 vs 570 — American 85-100 — G Genome-Wide Association Study 22533364
    rs303542 Intergenic 1.13 0.004840178 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs41383 NLRC5 — 0.00455 1173 vs 570 — American 85-100 — C Genome-Wide Association Study 22533364
    rs11943045 Intergenic 1.26 0.004524209 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs894558 NAV2 1.13 0.004524209 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs2596230 RYR3 1.21 0.004485855 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs1395451 Intergenic 1.19 0.004442126 801 vs 914 — Caucasian Median age 104 A C Genome-Wide Association Study 22279548

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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