Denigma

Longevity Variant Database

Narrow results by variant, study, or associated fields (e.g. gene symbol ADRB2):

Use ontology terms to further narrow results (e.g. aging, insulin, etc.):

  • Variant effect: + -
    Longevity‑Associated (1027)   No Age Effect (543)  
  • Study type: + -
    GWAS (2)   ‑ (27)   Candidate Region/Gene (784)   Meta‑Analysis (38)   Complete Mitochondrial Genome (2)   Whole‑Genome Linkage Scan (1)   Genome‑Wide Association Study (710)   Mitochondrial Haplogroup (36)   Mitochondrial genome (3)  
  • Variant type: + -
    SNP (572)   Locus (5)   Haplotype (87)   Other (1)   STR (11)   Deletion (5)   CNV (1)    (1)   VNTR (1)  
    • 1 2 3 4 5 6 7 8 9 10 11 12
    13 14 15 16 17 18 19 20 21 X Y MT
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    Populations | Study Types | Variant Types


    LVDB_word_cloud.png
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    variants.jpg
    polymorphism factor odds ratio pvalue initial number replication number Population age of cases shorter lived allele longer lived allele study type reference
    rs358256 GBA3 1.12 0.001136273 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs7656234 SLC4A4 1.16 0.000700593 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs2866164 MTTP 1.18 0.34 666 vs 540 1033 vs 359 German <100 G C Candidate Region/Gene 15911777
    rs1230155 METAP1 1.20 0.000611098 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs6812745 SORCS2 1.21 0.000558765 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs2660342 LOC285429 1.23 0.000314442 801 vs 914 — Caucasian Median age 104 A G Genome-Wide Association Study 22279548
    rs2069762 IL-2 1.43 0.096 168 vs 214 — Italian Centenarians G T Candidate Region/Gene 16518704
    -330T/G IL2 1.43 0.096 168 vs 214 — Italian >99 — — Candidate Region/Gene 16518704
    rs1517598 PROM1 1.44 0.000445256 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548
    rs4647992 NFKB1 1.81 0.000608192 801 vs 914 — Caucasian Median age 104 G A Genome-Wide Association Study 22279548

    The Longevity Variant Database (LVDB) is a collaborative effort to catalogue all published genetic variants relevant to human longevity.

    The project is directed by the Health Extension Research Foundation [http://www.healthextension.co/about/], and the online content is managed by the members of the Global Computing Initiative.

    LVDB is driven by an international collaboration of scientists, programmers, and volunteers, including Joe Betts-LaCroix, Kristen Fortney, Daniel Wuttke, Eric K. Morgen, Nick Schaum, John M. Adams, Jessica Choi, Barry Goldberg, Amir Levine, Maria Litovchenko, Aiste Narkeviciute, Emily Quist, Navneet Ramesh, Justin Rebo, Dmitri Shytikov, and Jimi Vyas. o

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