There were no significant single-SNP associations with longevity after correction for multiple testing via permutation tests. However, there was an observed association with longevity involving the GTCT haplotype of SNPs rs915179, rs2485662, rs4641, and rs1468772
Ethnicity:American,
Caucasian Age of cases: Mean age 101.5 Longer lived allele: GTCT Finding: Positive
Statistics - Number of cases/controls: 873 vs 443 (initial)
| New England Centenarian Study (NECS) (N = 738), (ii) the Southern Italian Centenarian Study (SICS) (N = 905), (iii) France (N = 1103), and (iv) the Einstein Ashkenazi Longevity Study (N = 702) (replication) - Odds ratio: 1.56 - Odds ratio type: Longer - p-value:
2.5e-05
[0.000025]
- Significant: Yes
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