|Heterozygous Gh1 anti-sense transgene ||Animals carrying a single copy of an anti-sense Gh1 transgene (tg/-) live on average 7-10% longer. tg/- animals are dwarfs and exhibit reduced levels of serum IGF1 . ||Rat ||+7 to +10 ||— ||— |
|Homozygous Gh1 anti-sense transgene ||Animals carrying two copies of a Gh1 anti-sense transgene (tg/tg) have a slighlty shorter lifespan (by 5-10%) compared to -/- animals. tg/tg animals are dwarfs and exhibit reduced levels of serum IGF1 . ||Rat ||-5 to -10 ||— ||— |
|SGS101 antisense RNAi ||Antisense RNA interference of SAG101 in transgenic plants delays the onset of leaf senescence for approximately 4 days . ||— ||— ||— ||— |
|PLD alpha antisense ||Antisense suppression of PLD alpha retards abscisic acid- and ethylene-induced senescence. Leaves detached from PLD alpha-deficient transgenic plants when inbutated in abscisic acid and ethylene exhibit a slower rate of senescence that those from wild-type and transgenic controls. PLD alpha deficient strains are associated with retardation of senescence as evidenced by delayed leaf yellowing, lower ion leakage, greater photosynthetic activity, and higher content of cholorophyl and phospholipids .
Antisense suppression of PLD alpha does not affect natural plant growth and development . ||— ||— ||— ||— |