| YVH1 deletion | Deletion of YVH1 increases replicative lifespan by 50% in the alpha strain [18340043]. | Yeast | +50 | — | — |
| OSH3 deletion | Mean replicative lifespan of OSH3 deletion mutant is not significant different from wild type [Fusheng, unpublished]. | Yeast | — | — | — |
| GAD1 deletion | GAD1 deletion extends replicative lifespan [21371425]. | Yeast | — | — | — |
| UGA4 deletion | Deletion of UGA4 does not effect replicative lifespan [21371425]. | Yeast | — | — | — |
| CTF8 deletion | Deletion of CTF8 increases mean chronological lifespan by 15-92% (15, 18, 42, 45, 92) in diploid cells [21447998]. | Yeast | +15 to +92 | — | — |
| LEU3 deletion | LEU3 deletion dramatically increases chronological lifespan [19302372]. | Yeast | — | — | — |
| YSC84 deletion | Deletion of YSC84 increases replicative lifespan by 20% in the alpha strain [19030232]. YSC84 deletion increases replicative lifespan by 25% in the alpha strain [18340043]. | Yeast | +20 to +25 | — | — |
| YPT6 deletion | Deletion of YPT6 increases replicative lifespan by 20% [19030232]. YPT6 deletion increases replicative lifespan by 30% in the alpha strain and by 10% in the a strain [18340043]. | Yeast | +10 to +30 | — | — |
| YME1 deletion | Deletion of YME1 decreases chronological lifespan by 50% [17492370] as well as replicative lifespan by 45% in the alpha strain [18340043]. | Yeast | -45 to -50 | — | — |
| VHS1 deletion | Deletion of VHS1 increases replicative lifespan [16293764]. VHS1 deletion increases replicative lifespan by 60% in the alpha strain [19030232]. | Yeast | +60 | — | — |
| VAM3 deletion | Deletion of VAM3 decreases mean replicative lifespan by 56% both on AL [19030232] and on moderate DR [18690010] (in BY4742/alpha strain). | Yeast | -56 | — | — |
| TMA19 deletion | Deletion of TMA19 increases median replicative lifespan by 16% (P<0.02) [16806052]. TMA19 deletion increases mean replicative lifespan by 25-30% in the alpha and a strains [19030232]. | Yeast | +25 to +30 | +16 | — |
| TIF4631 deletion | Deletion of TIF4631 increases replicative lifespan by 20% in the alpha and a strains [18340043].
TIF4631 increases replicative lifespan by 10-20% in the alpha and a strains [19030232]. | Yeast | +10 to 20 | — | — |
| TIF1 deletion | Deletion of TIF1 increases replicative lifespan by 20% in the alpha strain [19030232]. TIF1 deletion increases by 30% in the alpha strain and 15% in the a strain [18340043]. | Yeast | +15 to +30 | — | — |
| SWF1 deletion | Deletion of SWF1 decreases replicative lifespan by 30% in the alpha strain [19030232; 18340043]. | Yeast | -30 | — | — |
| RPS6B deletion | RPS6B deletion increases mean replicative lifespan by about 30% [16293764]. Deletion of RPS6B, but not of the RPS6A paralog increases replicative median lifespan robustly by 45% [17174052]. | Yeast | +30 | +45 | — |
| RPS6A deletion | Deletion of RPS6A increases replicative lifespan by 30% in alpha strain [18423200; 18340043]. | Yeast | +30 | — | — |
| RPS27B deletion | Deletion of RPS27B decreases mean replicative lifespan decreased by 20 - 30% in the alpha strain [18423200; 19030232] and by 27% in the ORF collection as well as by 14% in the remade strain [22377630]. | Yeast | -14 to -30 | — | — |
| RPL9B deletion | Deletion of RPL9B increases replicative lifespan by 30% in a strain [18423200; 18340043]. | Yeast | +30 | — | — |
| RPL9A deletion | Deletion of RPL9A increases replicative lifespan by 30% in the alpha strain and 20% in a strain [18423200; 18340043]. | Yeast | +20 to +30 | — | — |
| RPL4A deletion | Deletion of RPL4A increases replicative lifespan by 15% in the alpha strain [18340043]. RPL4A deletion increases replicative lifespan by 20% in the alpha strain [18423200]. | Yeast | +15 to +20 | — | — |
| RPL37B deletion | Deletion of RPL37B increases replicative lifespan by 35% in the alpha strain [18423200]. RPL37B deletion increases replicative lifespan by 35% in the alpha strain and 30% in a strain [19030232]. | Yeast | +30 to +35 | — | — |
| RPL10 deletion | Heterozygosity for RPL10 deletion increases median replicative lifespan by 24% [17174052]. | Yeast | — | +24 | — |
| RAD50 deletion | RAD50 mutations result in a 70% reduced replicative lifespan [10207108]. | Yeast | -70 | — | — |
| PIB1 deletion | Deletion of PIB1 increases replicative lifespan by 25% in the alpha strain [16293764; 19030232]. | Worm | +25 | — | — |
GenAge
GenDR
