Denigma

nrh-49 mutation

Species: Nematode (Taxid: 6239)
Factor: nhr-49
Manipulation: Loss-of-Function, Knockout, Mutation
Effect:

A mutant allele, nhr(nr2041) results in a short lifespan. nhr-49 mutant animals accumulate fat, due to decreased expression of enzymes involved in fatty acid beta-oxidation [15719061].


References:
  • 15719061: Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Edit / Update (Admin) | Delete

    Comment on This Data Unit