Denigma

EcR mutation

Species: Fruit fly (Taxid: 7227)
Factor: EcR
Manipulation: Loss-of-Function, Mutation
Effect:

Mutant heterozygotes in EcR live on mean 40%-50% longer than controls [12610309; reviewed in 12610294]. Homozygous mutants in EcR are inviable. The developmental time and weight of EcR+/- mutants is the same as control, but resistance to temperature, oxidative stress, and starvation is increased in heterozygotes [12610309].

Mean: +40 to +50

References:
  • 12610309: Steroid control of longevity in Drosophila melanogaster.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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