Denigma

rsks-1 RNAi

Species: Nematode (Taxid: 6239)
Factor: rsks-1
Manipulation: Loss-of-Function, Knockdown, RNA Interference
Effect:

RNA interference reducing S6K (rsks-1) mRNA levels by about two-fold extends mean lifespan 13-47% and maximum lifespan by up to 60%. The effect was also observed in daf-16 mutants and sir-2.1 mutants but not in daf-2 mutants [17266679].

Mean: +13 to +47
Maximum: +60

References:
  • 17266679: Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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