Denigma

ISC1 deletion

Species: Budding yeast (Taxid: 4932)
Factor: ISC1
Manipulation: Loss-of-Function, Knockout, Mutation, Deletion
Effect:

ISC1 deletion decreases chronological lifespan [21707788; 21707788]. CTA1 overexpression partially suppresses the shortened lifespan by ISC1. Deletion of SIT4 totally rescues the short lifespan of ISC1 mutants [21707788]. HOG1 deletion partially suppresses the premature aging phenotype and short lifespan of ISC1 deletion [22445853].


Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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