Denigma

rpr overexpression

Species: Fruit fly (Taxid: 7227)
Factor: rpr
Manipulation: Gain-of-Function, Overexpression
Effect:

Flies with ablated wings caused by overexpressing reaper (UAS-rpr) with a wing-specific Gal4 enhancer trap (1096-Gal4) exhibit only a 14% extension in lifespan compared to controls which exhibit a 61% extension upon DR [22768842].


References:
  • 22768842: Intramyocellular fatty-acid metabolism plays a critical role in mediating responses to dietary restriction in Drosophila melanogaster.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

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