| GSTM1 | glutathione S-transferase mu 1 | GSTM1 was not found to be associated with longevity [11162685]. | Human |
| INS | insulin | INS was not found to be associated with longevity [19367319]. | Human |
| INSR | insulin receptor | 5 intronic and 1 exonic polymorphisms in the INSR gene were examined in 122 semisupercentenarians (older than 105, 107 female, 15 male, mean age 106.8 years) and 122 healthy younger controls (105 female, 17 male, mean age 33.33). One haplotype, which was comprised of 2 intronic SNPs in linkage disequilibrium, was more frequent in semisupercentenarians than in younger controls [15582274].INSR was found to be associated with longevity [15582274]. INSR was not found to be associated with longevity [15582274]. INSR was not found to be associated with longevity [19489743]. | Human |
| TP53 | tumor protein p53 | A naturally occuring allele with decreased p53 activity has been assoicated with extended survival [15732191].TP53 was found to be associated with longevity [23125046]. TP53 was found to be associated with longevity [18256523]. TP53 was found to be associated with longevity [15621215]. TP53 was found to be associated with longevity [18256523]. TP53 was not found to be associated with longevity [15195682]. TP53 was not found to be associated with longevity [15621215]. | Human |
| APOB | apolipoprotein B (including Ag(x) antigen) | A sample of 143 centenarians and a control sample of 158 individuals were examined for polymorphism in APOB restriction fragment length (RFLP) (XbaI2488 and EcoRI4154) and variable number of tandem repeat (VNTR) (3'APOB-VNTR) polymorphisms. Neither the XbaI-RFLP nor the EcoRI-RFLP was able to discriminate between centenarians and controls, while the 3'APOB-VNTR multiallelic system revealed significant differences between the samples: the frequency of alleles with fewer than 35 repeats was lower in centenarians than in controls [9050915].apoB was found to be associated with longevity [17393087].APOB was found to be associated with longevity [15028112]. APOB was found to be associated with longevity [17393087]. APOB was not found to be associated with longevity [17393087]. APOB was found to be associated with longevity [9050915]. APOB was not found to be associated with longevity [11592926]. APOB was not found to be associated with longevity [8018664]. APOB was not found to be associated with longevity [9050915]. | Human |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | A/G ApaI site SNP in the IGF2 gene was examined in 224 older (75 years) Jewish Jerusalem residents of Ashkenazi ethnicity (150 males and 74 females) and a group of 441 younger subjects (22 years). An increase in the A allele was observed in older Ashkenazi females and a highly significant increase was observed in the AA genotype in these subjects [15621215].IGF2 was found to be associated with longevity [19367319]. IGF2 was not found to be associated with longevity [19367319]. IGF2 was found to be associated with longevity [17989723]. IGF2 was found to be associated with longevity [15621215]. | Human |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | ABCA7 was not found to be associated with longevity [22445811]. | Human |
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 | ABCC8 was not found to be associated with longevity [21612516]. | Human |
| ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | ACE was not found to be associated with longevity [12634288]. | Human |
| ACTN3 | actinin, alpha 3 | ACTN3 was not found to be associated with longevity [21407828]. | Human |
| ADARB2 | adenosine deaminase, RNA-specific, B2 | ADARB2 was found to be associated with longevity [20011587]. ADARB2 was not found to be associated with longevity [20011587]. | Human |
| ADCY5 | adenylate cyclase 5 | ADCY5 was not found to be associated with longevity [23020224]. | Human |
| ADIPOQ10 | adiponectin, C1Q and collagen domain containing | ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [23339001]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was found to be associated with longevity [18511746]. ADIPOQ was not found to be associated with longevity [18765803]. | Human |
| ADIPQO | adiponectin, C1Q and collagen domain containing | ADIPQO was not found to be associated with longevity [20201642]. ADIPQO was found to be associated with longevity [20201642]. | Human |
| ADRB1 | adrenergic, beta-1-, receptor | ADRB1 was not found to be associated with longevity [23020224]. | Human |
| ADRB2 | adrenergic, beta-2-, receptor, surface | ADRB2 was found to be associated with longevity [23020224]. ADRB2 was not found to be associated with longevity [23020224]. | Human |
| AFX | forkhead box O4 | AFX was not found to be associated with longevity [19489743]. | Human |
| AGTR1 | angiotensin II receptor, type 1 | AGTR1 was found to be associated with longevity [22569962]. AGTR1 was not found to be associated with longevity [22569962]. | Human |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | AKT1 was found to be associated with longevity [19489743]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was found to be associated with longevity [22929028]. AKT1 was not found to be associated with longevity [22929028]. | Human |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | AKT2 was not found to be associated with longevity [19489743]. | Human |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) | AKT3 was not found to be associated with longevity [19489743]. | Human |
| ANKRD19 | ankyrin repeat domain 19, pseudogene | ANKRD19 was not found to be associated with longevity [21612516]. | Human |
| APOE + TOMM40 | — | APOE + TOMM40 was not found to be associated with longevity [21418511]. APOE + TOMM40 was not found to be associated with longevity [23040522]. | Human |
| ATF4 | — | ATF4 was not found to be associated with longevity [23770741]. | Human |
| ATXN1 | ataxin 1 | ATXN1 was not found to be associated with longevity [21612516]. | Human |
