ZWINT | ZW10 interactor | ZWINT was found to be associated with longevity [22279548]. | Human |
ZNF331 | zinc finger protein 331 | ZNF331 was found to be associated with longevity [21782286]. | Human |
ZBTB20 | zinc finger and BTB domain containing 20 | ZBTB20 was found to be associated with longevity [22279548]. | Human |
XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | XRCC5 was found to be associated with longevity [22406557; 16518718]. | Human |
XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | XRCC4 was found to be associated with longevity [16518718]. | Human |
XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | XRCC3 was found to be associated with longevity [16518718]. | Human |
XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | XRCC1 was found to be associated with longevity [16518718]. | Human |
XKR6 | XK, Kell blood group complex subunit-related family, member 6 | XKR6 was found to be associated with longevity [22279548]. | Human |
XDH | xanthine dehydrogenase | XDH was found to be associated with longevity [22406557; 22279548]. | Human |
WWOX | WW domain containing oxidoreductase | WWOX was found to be associated with longevity [22279548]. WWOX was found to be associated with longevity [24244950]. | Human |
WDR72 | WD repeat domain 72 | WDR72 was found to be associated with longevity [22279548]. | Human |
VWA5A | von Willebrand factor A domain containing 5A | VWA5A was found to be associated with longevity [21782286]. | Human |
VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) | VPS13D was found to be associated with longevity [22279548]. | Human |
Vitamin D receptor | vitamin D (1,25- dihydroxyvitamin D3) receptor | Vitamin D receptor was not found to be associated with longevity [21051524]. | Human |
VEGFA | vascular endothelial growth factor A | VEGFA was found to be associated with longevity [17574707]. VEGFA was not found to be associated with longevity [17574707]. | Human |
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | VDR was found to be associated with longevity [21051524]. VDR was not found to be associated with longevity [20407924]. VDR was found to be associated with longevity [20407924]. | Human |
VASH1 | vasohibin 1 | VASH1 was found to be associated with longevity [22279548]. | Human |
upstream of FOXO3A | — | upstream of FOXO3A was found to be associated with longevity [19196970]. | Human |
Upstram of FOXO3A | — | Upstram of FOXO3A was found to be associated with longevity [19196970]. | Human |
UCP3 | uncoupling protein 3 (mitochondrial, proton carrier) | UCP3 was found to be associated with longevity [22743239]. UCP3 was found to be associated with longevity [22743239]. UCP3 was found to be associated with longevity [22743239]. UCP3 was found to be associated with longevity [22743239]. UCP3 was found to be associated with longevity [22743239]. UCP3 was found to be associated with longevity [22743239]. | Human |
UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) | UCP1 was found to be associated with longevity [21827845]. | Human |
UCK2 | uridine-cytidine kinase 2 | UCK2 was found to be associated with longevity [22445811]. | Human |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | UCHL1 is assoicated with Parkinson's disease [9774100]. UCHL1 belongs to a family of de-ubiquitinating enzymes responsible for the hydrolysis of bonds between ubiquitin molecules and small adducts [11084366]. Decreased activity due to mutation may result in decreased labeling of abnormal proteins for clearance. | Human |
SOD1 | superoxide dismutase 1, soluble | Ubiquitous overexpression of SOD1 does not extend lifespan in mice. Homozyous transgenic mice with two- to five-fold overexpression of SOD1 in various tissues exhibit a light reduction in lifespan. Hemizygous transgenic mice, with 1.5- to 3-fold overexpression of SOD1 display no difference in lifespan compared with nontransgenic litermate controls [10719757]. Transgenic mice with a mutant SOD1 transgene develop neuronal cytoskeletal lesions resembling the human amytrophic lateral sclerosis (ALS) phenotype [8610185]. Transgenic mice overexpressing SOD1 (and having 3.1-fold higher cellular Cu,Zn SOD activity in the brain) have reduced infarct size following experimental cerebral ischemia [1763030].SOD1 was not found to be associated with longevity [24163049]. | Human |
UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | UBE2H was found to be associated with longevity [22279548]. | Human |