Denigma

rsr-1

Symbol: rsr-1
Name: SR protein related 1
Alias: SR protein related family member (rsr-1);WBGENE00004706
Entrez gene ID: 173013
Ensembl gene ID: F28D9.1
Species: Worm (Taxid: 6239)

Functional description:
Protein RSR-1; SR protein related family member (rsr-1) [Source:RefSeq peptide;Acc:NP_492875] [Ensembl]; rsr-1 encodes the C. elegans homolog of the SRm160 (serine/arginine-repeat related nuclear matrix protein of 160kDa) splicing coactivator; rsr-1 is an essential gene that is required for development, including normal pharyngeal morphology. [WormBase]

Observation:

rsr-1 RNAi in the adulthood extends the mean lifespan by 6% without an effect on maximum lifespan [23144747].



Interventions:
  • rsr-1 RNAi +6.1% 0%

    • Assays: Organismal Lifespan
    Mean: +6.1
    Maximum: 0

    Classification:
  • Gerontogene
  • Positive Gerontogene


    • References:
  • 23144747: Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks.


    • Aging Relevance Analysis/Source:
  • GenAge
  • GenDR

    • Homologs
  • SRRM1 (9606)
  • SRRM1 (9598)
  • SRRM1 (9615)
  • SRRM1 (9913)
  • Srrm1 (10090)
  • Srrm1 (10116)
  • SRRM1 (9031)
  • srrm1 (7955)
  • SRm160 (7227)
  • AgaP_AGAP005366 (7165)
  • rsr-1 (6239)
  • AT2G29210 (3702)



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